Understanding Diseases in Human Body through Knockout Genes – Part 2

Wednesday, October 27, 2021

Gene knockout (credit to YouTube)

You may read Part 1:


The knockout will result in disrupt of targeted gene.


Since mouse is closely related to humans, thus, it is favorite animal for knockout experiments.


Especially with regard to genetic questions that relate to human physiology or behaviors.


At Figure above (top of this article), we can see how to target gene.


The introduce specific gene modification in mice by the use of embryonic stem (ES) cell, then produced knockout animal (mice).


As described by Hansson (2007) that knockout have become absolutely important in medical research.


Through targeting (removing) a specific gene, we can find out what happens once it is gone.


Little plant in the early autumn


It is lead to new understanding of normal development and disease processes, then identified new avenues for medical therapy.


# Previous postings:


References

Hansson, GK. 2007. ADVANCED INFORMATION. Gene modification in mice.

"The Nobel Prize in Physiology or Medicine 2007".


NIH (National Human Genome Research Institute). 2015. Knockout Mice.

36 comments:

  1. Replies
    1. Thanks to visit my blog-
      Understanding Diseases in Human Body through Knockout Genes – Part 2

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    2. Understanding Diseases in Human Body through Knockout Genes – Part 2

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  2. Replies
    1. Thanks to visit my blog-
      Understanding Diseases in Human Body through Knockout Genes – Part 2

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    2. Understanding Diseases in Human Body through Knockout Genes – Part 2

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  3. Replies
    1. Thanks to visit my blog-
      Understanding Diseases in Human Body through Knockout Genes – Part 2

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  4. Interesting, thanks for sharing.

    ReplyDelete
    Replies
    1. Thanks to visit my blog-
      Understanding Diseases in Human Body through Knockout Genes – Part 2

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  5. I'm waiting for more stem cell research for autoimmune diseases. Once they have a breakthrough on T cells hopefully they will be able to cure so many diseases. Thanks for sharing!

    ReplyDelete
    Replies
    1. Yes, we hope so...

      Thanks to visit my blog-
      Understanding Diseases in Human Body through Knockout Genes – Part 2

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  6. It is fascinating how genetic manipulation may be used to cure diseases! Thank you for the informative post. God bless.

    ReplyDelete
    Replies
    1. we wait another breakthrough

      Thanks to visit my blog-
      Understanding Diseases in Human Body through Knockout Genes – Part 2

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  7. It is amazing what can be discovered and created today!

    ReplyDelete
    Replies
    1. Indeed....

      Thanks to visit my blog-
      Understanding Diseases in Human Body through Knockout Genes – Part 2

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  8. Beautiful, thanks for sharing :)

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    ReplyDelete
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      Understanding Diseases in Human Body through Knockout Genes – Part 2

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  9. it is just amazing what they are learning

    ReplyDelete
    Replies
    1. Thanks to visit my blog-
      Understanding Diseases in Human Body through Knockout Genes – Part 2

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  10. Interesting and informative.
    Have a nice day ♥

    Ann
    https://roomsofinspiration.blogspot.com/

    ReplyDelete
    Replies
    1. Thanks to visit my blog-
      Understanding Diseases in Human Body through Knockout Genes – Part 2

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  11. Thanks for sharing this interesting and informative post.

    ReplyDelete
    Replies
    1. Thanks to visit my blog-
      Understanding Diseases in Human Body through Knockout Genes – Part 2

      Delete
  12. Medical research is very challenging. A lot goes into all these technology and I am thankful to be living in this era. I hope the shoots get to grow before winter arrives

    ReplyDelete
    Replies
    1. we are lucky generation...


      Thanks to visit my blog-
      Understanding Diseases in Human Body through Knockout Genes – Part 2

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  13. Very ınteresting... thanks for your sharing:)

    ReplyDelete
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    1. Thanks to visit my blog-
      Understanding Diseases in Human Body through Knockout Genes – Part 2

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  14. Very interesting information. Thanks for sharing.

    Have a nice week!

    ReplyDelete
    Replies
    1. Thanks to visit my blog-
      Understanding Diseases in Human Body through Knockout Genes – Part 2

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  15. Yes this is really close, so I can go there when I go for a little walk :D
    Thank you, I like my new products too.
    Have a wonderful new week

    Very interesting post, thanks for sharing.
    Our technology is so amazing, how we know even more and more about diseases and so on.

    ReplyDelete
    Replies
    1. I see...

      Thanks to visit my blog-
      Understanding Diseases in Human Body through Knockout Genes – Part 2

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  16. Replies
    1. Thanks to visit my blog-
      Understanding Diseases in Human Body through Knockout Genes – Part 2

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  17. I wish they discover the cure for my illness!
    xoxo

    marisasclosetblog.com

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      Understanding Diseases in Human Body through Knockout Genes – Part 2

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